Miranda Hart, Graham Norton, and Sarah Millican have also been shortlisted for the publicly-voted prize, Channel 4 has announced.
Hart was last year’s winner, beating fellow nominee Mitchell, while Fresh Meat star Whitehall was nominated for 'Best Male Comedy Breakthrough Artist' and Millican was in the 'Best Female TV Comic' category.
Jonathan Ross, who will host the event, said: "I've tried, but I can't think of a more entertaining way to spend a winter's evening than watching a room full of our best and brightest comedians get slowly drunk while they wait to see which of their rivals picks up an award. Surely that's what Christmas is all about?
"To be hosting it again, for what feels like the 87th time, is also an honour and privilege and I will do my best, like the Batman facing a room full of Jokers, to keep things running smoothly."
Copyright Speakers Corner 2016